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Pragmatic trials are those that are designed to provide information for real-world clinical practice. They are often focused on practical aspects of the study design, including the recruitment process and consent, adherence, and the use of commonly available equipment.

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Pragmatic, a software company offers a range of casino games to online gambling platforms. Pragmatic's iGaming software is used by top operators and land based casinos. The company provides front-end design tools, analysis tools, promotions, marketing, payment systems, security, customer service and bug reporting. The company also provides an environment that is safe and secure with high-quality graphics, gameplay and security.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and had participants from different geographic areas. This type of heterogeneity which is essential for pragmatic trials to be valid and reduce bias in results is also essential. However, too much heterogeneity could cause issues with the design of the trial.

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The goal of pragmatic trials is to simulate real-life scenarios and to achieve maximum credibility externally. They are typically commissioned by practitioners and policy makers to guide their decision-making. They can also be a great method of determining the causal relationship between the intervention and its effects. However, they should not be used as a substitute for the use of explanation studies.

The pragmatism concept is controversial and there are doubts about whether pragmatic trials should replace or complement them. Schwartz and 프라그마틱 홈페이지 Lellouch1 suggested the distinction between explanatory trials, which prove the validity of a clinical or physiological hypothesis and pragmatic trials, which inform policy and practice decisions. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the elements of a pragmatic research study which includes the recruitment, design, and delivery of the intervention, and follow-up.

The number of pragmatic trials is growing. A recent Medline search using the keywords naturalistic and pragmatic, limited to controlled trials randomized to control (RCTs) produced 34 articles, as shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. It is important to note, however, that the majority were conducted in primary-care settings.