Nterest the fact that most patients come from the Far East > 자유게시판

Nterest PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/11879011 the fact that most patients come from the Far East region [4]. It is unknown weather environmental conditions, geographic and local factors or dietary habits predispose to this form of disease. The role of the uropathologist is of utmost importance for a correct diagnosis to be established. Histologically, the SCC-UP is usually admixed with other malignancies, mainly transitional cell carcinoma (TCC) and rarely with squamous cell carcinoma, adenocarcinoma and sarcoma [5,8]. On light microscopy, small cell carcinoma is consisted of small, round or oval shaped cells, with a prominent nucleus, scant cytoplasm and granularConclusionIrrespectively of the treatment administered, SCC-UP patients face a dismal prognosis. The majority of themPage 3 of(page number not for citation purposes)Cases Journal 2009, 2:http://casesjournal.com/casesjournal/article/view/die within a year after the initial diagnosis [4,6,7]. Currently, debulking treatment associated with CMT could offer some survival benefit in selected patients [4]. In the future, targeted molecular therapy might radically change our therapeutic approach and improve survival of the patients with rare type of malignancy [10].5. 6.7. 8.AbbreviationsSCC, small cell carcinoma; IVU, intravenous urography; CT, computed tomography; Tur-BT, transurethral resection of the bladder tumor; Syn, synaptophysin; Chr, chromogranin; CMT, chemotherapy; SCC-UP, small cell carcinoma of the ureter and pelvis; TCC, transitional cell carcinoma; NSE, neuron specific enolase; uUC, undifferentiated urothelial carcinoma; LCA, leukocyte common antigen; SCC-B, SCC of the bladder.9. 10.Shimasaki N, Inoue K, Nishigawa H, Kuroda N, Shuin T: Combined small cell carcinoma and sarcomatoid squamous cell carcinoma in the renal pelvis. Int J Urol 2005, 12:686-689. Busby JE, Brown GA, Tamboli P, Kamat AM, Capecitabine Dinney CP, Grossman HB, Martin SF: Upper urinary tract tumors with non transitional histology: a single-center experience. Urology 2006, 67:518-523. Chuang CK, Liao SK: A retrospective immunohistochemical and clinicopathological study of small cell carcinomas of the urinary tract. Chang Gung Med J 2003, 26:26-33. Tsutsumi M, Kamiya M, Sakamoto M, Tobisu K, Kakizoe T: A ureteral small cell carcinoma mixed with malignant mesodermal and ectodermal elements: a clinicopathological, morphological and immunohistochemical study. Jpn J Clin Oncol 1993, 23:325-329. Sved P, Gomez P, Manoharan M, Civantos F, Soloway MS: Small cell carcinoma of the bladder. BJU Int 2004, 94:12-17. Yao JL, Madeb R, Bourne P et al.: Small cell carcinoma of the prostate: an immunohistochemical study. Am J Surg Pathol 2006, 30:705-712.ConsentThe authors have repeatedly made efforts to come in contact with his only relative alive (his nephew), either by phone or by mail, but it was fruitless. As far as we know, he had no other relatives alive. No reference to personal data is made in the submitted article and images. The privacy of the patient has been fully protected.Competing interestsThe authors declare that they do not have any competing interests.Authors' contributionsDK is responsible for the concept, the writing of the paper and the submission. He was present in the operation theater during the nephroureterectomy. He collected the patient's data. PP is responsible for the preparation of the images, the review of the literature and he was present in the operation theater when transurethral resection of the tumors was performed. SS performed a crit.