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Mesothelioma - What Causes Mesothelioma?

Like all cancers, mesothelioma's symptoms are similar to those of other diseases. Early diagnosis and treatment can improve the prognosis of a patient.

Asbestos exposure is the main cause of mesothelioma. Asbestos is made up of a group of minerals that can be broken down into long, thin fibres. Asbestos fibres can become stuck in certain organs after being inhaled or eaten.

Exposure to Asbestos

Exposure to asbestos is the most proven cause of Mesothelioma. Asbestos is a mineral that occurs naturally is made up of strong and microscopic fibers. It was widely used in automobiles, buildings, and a myriad of construction materials from the 1930s to the early 1980s due to the fact that it resisted fire, water and sound. The makers of asbestos-based materials were aware of the dangers it poses to health, but they did not inform the public.

The most risky exposure was for those who worked directly with or handled asbestos-containing products. Mining ships, asbestos removal and other industrial jobs exposed workers to large amounts of asbestos. Asbestos-containing products such as pipes, shingles, and glues, as well as talcum powder were used in the home by people who were also exposed. In the United States, chrysotile asbestos is the most popular type of asbestos used. Other types of asbestos like amosite or Crocidolite have also been linked to mesothelioma.

The signs of mesothelioma generally do not appear for decades after exposure to asbestos. When symptoms begin to manifest, the disease can quickly advance and become fatal. The lungs are the ones most often affected (pleural mesothelioma), but it can also affect the lining of your stomach, heart, or testicles.

Asbestos fibres that are inhaled or consumed adhere to the cells that line internal organs and tissues. As time passes, this causes genetic mutations that lead to cancer. The mutated cells multiply uncontrollably and form tumors.

People who work in industries that have a high exposure to asbestos are at higher chance of developing mesothelioma than those who do not. Men who worked in blue-collar jobs or were in the military are at greatest risk. Women who were exposed to asbestos can develop mesothelioma. This is especially true if their family members were exposed in the workplace.

Secondary exposure can occur when a person who is at risk of developing mesothelioma brings asbestos fibers home on their clothing and other clothing. This has been the case for spouses of those exposed to asbestos as well as hairdressers and ceramics workers. Certain studies have demonstrated that a mineral known as Erionite, which is akin to asbestos, may increase the chance of developing mesothelioma. However it has not been confirmed by other studies.

Exposure to minerals

Mesothelioma is mesothelioma only caused by asbestos a result of the transformation of cells that line specific areas of the body, such as the lining of the chest (pleura) and abdominal cavities. Mesothelioma may also develop in the linings of the heart (pericardium) or testicles. The disease is usually associated with asbestos exposure, but other causes can also be responsible.

Asbestos is a natural mineral made up of strong, microscopic fibers. It was utilized in building materials, automobile brakes, and a variety of other products from the 1930s through the 1980s, due to its resistance to water, fire, and sound. Many workers in the field of construction or military were exposed to asbestos. Workers who handled and removed asbestos were susceptible to breathing the dangerous particles.

The specific risk of mesothelioma is different based on the job, but any asbestos exposure increases the chances of developing the disease. Mesothelioma is linked to a wide range of occupations, but it most commonly is a problem for miners, millers and shipyard workers, as well as asbestos manufacturers. It has also been discovered among those working on the production of automobiles and aircraft, as well as those who handled or removed insulation.

The onset of mesothelioma generally slow, but it can take between 20 and 60 years before symptoms begin to show after asbestos exposure. Even if you've never worked with asbestos, it is important to speak to your doctor regarding mesothelioma. The earlier the cancer is identified the more likely it will be to treat successfully.

In the past, many who developed mesothelioma did not be diagnosed until their disease was progressing. Mesothelioma is a rare form of cancer, which is why doctors often overlook the signs, such as persistent coughing or difficulty breathing.

Asbestos was phased out by the 1980s. However those who worked in the military or in the industrial sector prior to this time are still at higher risk of mesothelioma. Researchers have recently discovered new types of mineral exposure which increase the risk of mesothelioma. In Turkey for instance, a mineral called erionite can be found in the soil and used in making materials. In studies of the local population exposed to erionite extensively men are more likely than women to develop mesothelioma. In Italy the same phenomenon has been observed with respect to another mineral called fluoroedenite.

Genetics

The mesothelium is afflicted by this kind of cancer. It is typically located in the lining of the chest cavity, but can also affect the tissue around the heart, abdomen and testicles.

Doctors have linked mesothelioma to the mutation in the gene known as BAP1. This gene regulates the process of putting calcium into cells. If it is altered, the person is at a greater risk chance of developing cancerous cells. Researchers have discovered that BAP1 mutants are present in 70 percent of patients with mesothelioma. This discovery has made it easier for doctors to recognize mesothelioma, and to increase screening for the disease, especially in people who have an ancestral history of asbestos exposure.

Researchers have also discovered other genetic mutations that could lead to the development of mesothelioma is a cancer caused by what (his comment is here). These mutations have made it easier for mesothelioma specialists to better know the disease and to treat it more effectively.

While genetics can play a role in malignant mesothelioma causes, asbestos is still the leading risk factor for the cancer. Certain people who are exposed to asbestos do not develop cancer, while those who do not have a genetic predisposition develop mesothelioma following a prolonged time period after exposure. Secondary exposure or paraoccupational asbestos exposure can be a result of coworkers who have been exposed to asbestos take fibers home on their clothing and skin.

In some cases mesothelioma is seen to run in families due to a combination of genetics as well as asbestos exposure. However, most mesothelioma cases appear to be random and don't appear to have any family histories of the disease.

Asbestos-related mesothelioma could be a serious illness. But, research continues to make significant progress in the treatment of patients and their treatment options. Asbestos is now banned in a number of countries across the globe and researchers are advancing mesothelioma treatments with more effective drugs, better specific surgeries, and more effective diagnostic tests. To learn more about these recent advances, request a free copy of the Mesothelioma Guide. This comprehensive resource contains an exhaustive list of treatment options for mesothelioma, including the most recent clinical trials and promising options. Download the guide by filling in our online form, or by calling directly.

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Mesothelioma affects the cells lining certain parts of the human body, including the abdomen and lungs. Most cases of mesothelioma start in the lining of the chest cavity (the pleura) but it can also occur in the abdomen's lining (the peritoneum) and around the heart (the pericardium).

While asbestos exposure is a primary risk factor, other factors such as age or gender can increase the risk of developing mesothelioma. Certain of these factors, like smoking or a person's gender, can be changed, while others, like family history or age, cannot.

The majority of people diagnosed with mesothelioma have a family history of the disease, and a lot of them have experienced long-term exposure to asbestos in their jobs. People diagnosed with pleural mesothelioma tend to be over 45 years old, and the majority of people suffering from mesothelioma of the peritoneal mesothelioma not caused by asbestos region are older than 65. This is due to the fact that mesothelioma can take decades to develop, and symptoms can begin to show up in an older person gets older.

A biopsy is among the tests that doctors use to determine if pleural mesothelioma is present. Other tests include the CT scan, FDG-positron emission tomography and CT scan. A biopsy is the process of removing the tissue for examination under a microscope, and mesothelioma is a Cancer caused by what is possible using VATS (Video-assisted thoracoscopic surgery) which is a kind of keyhole surgery; or a needle guided by the CT scan.

Doctors can test blood for a genetic mutation called BAP1. This is an error in the gene that inhibits the growth of tumours and makes one more prone to developing malignancies caused by environmental toxins. This mutation increases the risk of developing mesothelioma, even after relatively low levels asbestos exposure. It also decreases the duration of latency for people who have this mutation. However, researchers do not yet know how widespread this mutation is in the general population, or whether it is preventable by lifestyle choices, such as avoiding exposure to harmful substances. This is an area of ongoing research.